Etiological survey of severe HFRS patients
The blood samples were detected for HTNV and other viruses. The antigen
detection showed that 3 severe patients (No. 2, 5 and 6) were positive
for HTNV. All other detection assay pertaining to SEOV and other common
vector-borne infectious diseases were negative. DNA sequencing results
confirmed the presence of HTNV (Appendix 2). To further confirm the
pathogen, blood samples were subjected to virus isolation. Samples from
two patients (No. 5 and 6) were psotive for SFTSV, and no other common
vector-borne viruses were identified. DNA sequencing of the
amplification product confirmed the presence of SFTSV (Appendix 3).