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Avoiding artifactual components in summary metrics in Deep Brain Stimulation corrupted MEG data
  • +4
  • Suranjita Ganguly,
  • Ankita Jain,
  • Aditya Koppula,
  • Sreedev Sasidharan,
  • Vijay Mohan Vamsi Dattada,
  • Andreas Højlund,
  • Kousik Sarathy Sridharan
Suranjita Ganguly
Dept. of Biomedical Engineering, Indian Institute of Technology Hyderabad Hyderabad

Corresponding Author:[email protected]

Author Profile
Ankita Jain
Dept. of Biomedical Engineering Indian Institute of Technology Hyderabad Hyderabad
Aditya Koppula
Dept. of Biomedical Engineering Indian Institute of Technology Hyderabad Hyderabad
Sreedev Sasidharan
Dept. of Biomedical Engineering Indian Institute of Technology Hyderabad Hyderabad
Vijay Mohan Vamsi Dattada
Dept. of Biomedical Engineering Indian Institute of Technology Hyderabad Hyderabad
Andreas Højlund
Department of Linguistics, Cognitive Science and Semiotics, Aarhus University
Kousik Sarathy Sridharan
Dept. of Biomedical Engineering, Dept. of Heritage Science and Technology Indian Institute of Technology Hyderabad Hyderabad

Abstract

The surgical procedure or Deep Brain Stimulation (DBS) is an established technique aimed at neuromodulation and is most often used for treating neurological and neuropsychiatric disorders. In clinical studies, Magnetoencephalography (MEG) is a widely used technique for characterizing the effects of Deep Brain Stimulation (DBS). A significant limitation of DBS stimulation is the inability to distinguish stimulation artifacts from actual neuronal activity, especially in the lower frequencies, where it may obscure the biological response and be a confounding factor. This paper aims to understand how to circumvent the DBS artifactual component in the summary metrics of DBS-corrupted MEG data. To do the same, we used a watermelon as a phantom model of the head to deploy DBS electrodes. The spectral signature of the artifactual component of DBS and it's power in different clinically significant bands of interest were analyzed in the frequency domain. We present the preliminary results for the same in this paper.
02 Apr 2024Submitted to TechRxiv
02 Apr 2024Published in TechRxiv